Schistosoma antigens downregulate CXCL9 production by PBMC of HTLV-1-infected individuals
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چکیده
منابع مشابه
Schistosoma antigens downregulate CXCL9 production by PBMC of HTLV-1-infected individuals.
HTLV-1 is the causal agent of Adult T cell Leukemia/lymphoma (ATLL) and HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). The immune response to HTLV-1-infection is polarized to the Th1-type, and the presence of CXCL9/CXCL10 chemokines may lead to an increase in the recruitment of pro-inflammatory molecules in spinal cord tissue, contributing to the damage observed in the dev...
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Human T lymphotropic virus type 1 (HTLV-1) is the causal agent of myelopathy/tropical spastic paraparesis (HAM/TSP), a disease mediated by the immune response. HTLV-1 induces a spontaneous proliferation and production of pro-inflammatory cytokines by T cells, and increasing interferon-γ (IFN-γ) and tumor necrosis factor-α (TNF-α) levels are potentially involved in tissue damage in diseases rela...
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ژورنال
عنوان ژورنال: Acta Tropica
سال: 2017
ISSN: 0001-706X
DOI: 10.1016/j.actatropica.2016.12.030